Viscus© flywheel cycle ergometer. Used to study active-assisted recovery following total knee arthroplasty
PRINCIPAL INVESTIGATOR:
Simon J. Lees, Ph.D.
In the Skeletal Muscle Cell Biology Lab, we study several areas in biomedical research. We have a fully translational program with projects spanning cell-based research, pre-clinical animal models, and clinical/rehabilitation programs. These include:
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Studying the age-related loss of skeletal muscle mass, known as sarcopenia, and a diminished capacity for skeletal muscle regeneration.
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Investigating the influence of low-dose radiation on cell function.
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Determining the effects of in utero stress on metabolism.
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Examining mechanisms leading to improved glucose uptake and insulin sensitivity in peripheral tissues.
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Investigating brown adipose tissue metabolism using micro positron emission tomography (microPET).
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Leading multidisciplinary teams involving physicians, physiotherapists, occupational therapists, nurses, dietitians, and research assistants in the community, hospitals, and rehabilitation centres. These purpose of these projects is to establish evidence-based changes to standard of care. These include:
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Enhanced recovery programs following total joint arthroplasty
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Establishing new prehabilitation treatment protocols prior to total joint arthroplasty
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Establishing activity recovery programs to treat post-concussive syndrome
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Exploring novel combination cancer therapies using microPET.